This valuable study reports the conservation of sperm-egg envelope binding by demonstrating successful recognition of the micropyle in fish eggs by the mouse sperm. However, the evidence supporting ...

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Resurrection of ancient forms of CD4 reveals how retroviruses have placed selective pressure on this gene in apes, acting to propagate infection-resistant alleles.

Time-lapse analyses of millions of antibiotic-stressed Escherichia coli characterize the diverse single-cell dynamics of persister cells that depend on antibiotics, culture conditions, and ...

This important study provides insights into the role of maternal behavior in the learning and ontogeny of vocalization. It finds evidence that the maternal behavior of sac-winged bats (Saccopteryx ...

Experiments in fruit fly larvae show that epidermal cells can communicate with sensory neurons to drive responses to pain.

This fundamental study explores a novel cellular mechanism underlying the degeneration of locus coeruleus neurons during chronic restraint stress. The evidence supporting the overexpression of LC ...

Adolescent alcohol exposure reduced basolateral amygdala-driven inhibition of pyramidal neurons projecting from the prefrontal cortex to the periaqueductal gray and increased inhibition of prefrontal ...

Life has been announced as a winner in the first Crossref Metadata Awards, recognising its commitment to high-quality ...

This study provides a valuable extension of credibility-based learning research by showing how feedback reliability can distort reward-learning biases in a disinformation-like bandit task. Although ...

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

This study exploring the role of TRPV1 signaling in recruiting macrophages and promoting angiogenesis during tympanic membrane wound healing presents useful findings. However, the strength of evidence ...